The European NUCLEAR project, funded by the prestigious Marie Skłodowska-Curie Actions Doctoral Network, is excited to announce an open position in our lab!

NUCLEAR is dedicated to shaping the next generation of experts in the emerging field of Metabolic Regulation of Genome Function and Cell Identity. As part of this pioneering project, you’ll contribute to fundamental research in stem cell biology and cancer studies.

Join our international network of European leaders in metabolomics, functional genomics, chromatin regulation, and stem cell biology!

Continue reading “[Closed] PhD position: Metabolism as regulator of cell specification through epigenetic regulation in cancer”

Our latest research is now online! Huge congratulations to our PhD candidate Nguyen Thi Binh Nguyen for spearheading this amazing work! More than 100 years after the discovery of the Warburg effect, we uncover a new role for lactate in shaping tumor development by increasing the population of cancer stem cells through epigenetic regulation of MYC.

Seeing is believing! We performed advanced live imaging coupled with machine learning analysis of patient-derived tumor organoids, gaining unprecedented insights into how metabolic changes impact cancer cell identity.

A big shout-out to our fantastic collaborators: Oncode Institute Labs and Sander Tans and Jeroen van Zon Labs (AMOLF)! And to all team members of the Rodriguez Colman Lab.
Grateful for the support from KWF Kankerbestrijding (Young Investigator grant scheme) and NWO (Nederlandse Organisatie voor Wetenschappelijk Onderzoek) (VIDI) for supporting fundamental research.

Exciting times at UMC Utrecht – Center for Molecular Medicine!